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11 -15 mars 2024, Lund (Suède)


FASEM for Life Science:from experiments to data analysis

We propose a 5-day advanced school, called “FASEM (French-Swedish Academy for Scattering Experiments and Modeling) for Life Science: from experiments to data analysis".
The FASEM school will be held in Lund, Sweden, on March 11-15, 2024.

Following the success of the first FASEM edition (French and Swedish School on Energy Materials) in 2019, the French Neutron Society (SFN) decided to organize a second edition of this type of school. FASEM could ultimately become a recurring thematic school in different fields of application.

Goals and Objectives
The main objective of this advanced school is to train young researchers in biology, biophysics, pharmacology, etc. to the use of X-ray (XR) and neutron scattering structural techniques (crystallography, small-angle scattering, reflectometry), ranging from experiments to complete and in-depth analysis of the data, based on mathematical and modeling approaches (e.g. analytical fits, ab initio modeling, artificial intelligence, Bayesian and multimodal methods). The complementarity of these scattering techniques with other structural biology methods, such as NMR, will be considered as well.
Another objective of FASEM is to promote the use of XR and neutron large-scale facilities, which are not yet currently used in biology. The new European neutron source (ESS) in Lund, to be commissioned in 2025, and the 4th generation synchrotrons will lead to a significant breakthrough in scattering techniques, opening particularly interesting perspectives for structural biology. FASEM will take place in Lund in order to encourage French and Swedish researchers to explore the new possibilities offered by these resources. Therefore, the school will propose lectures (theory, hands-on, applications, highlights), discussion sessions, and visits to the MAX-IV and ESS, respectively XR and neutron sources in Lund.

The objectives are:
- Train young researchers, doctoral students, and post-doctoral fellows in biology and biophysics, eventually coming as well from related fields such as pharmacology, virology, food science, etc., interested in advanced techniques using XR and/or neutron scattering, with the aim to use the most relevant experimental techniques for their present or future
- Train participants to scattering and modelling tools to process, analyse, and interpret their experimental data and extract all possible information.
- Highlight the contribution of these techniques to the study of biological macromolecules and their complementarity with other methods of investigation in structural biology (NMR, cryo-EM, etc.).
- Create and strengthen links between the community of biologists (in the broad sense) and that of XR and neutron large-scale facilities.
- Develop and strengthen sustainable scientific exchanges between the French and Swedish communities on the use of large-scale facilities, in connection with the forthcoming ESS commissioning.