Post-Doctoral position, Pasteur Institute, Paris

*Intitulé du poste* :	Post-doc
*Ville* :	Paris
*Laboratoire/Institut* :	Institut Pasteur
Contexte :	A fully funded postdoc position is immediately available in the team of Ludovic Sauguet at the Pasteur Institute in Paris. Our goal is to study the structure and function of the archaeal replication machinery, which includes a new class of DNA polymerase that has been extensively studied in the lab. We use an integrative structural biology approach, primarily through Cryo-EM single particle analysis. The laboratory is situated in the main Pasteur Institute campus in Paris, which has access to an outstanding range of facilities and equipment, including a state-of-the-art Titan Krios and two Glacios electron microscopes equipped with Falcon 4i direct detectors and Selectris energy filters. Training in sample preparation and microscope operation will be provided if necessary. The position is secured for two years, and support will be provided to find funding to further extend the contract. The project is funded by an ANR grant (National Research Agency) and will be carried out in close collaboration with the group of Dr. Ghislaine Henneke, at the “Laboratoire de Microbiologie des Environnements Extrêmes (LMEE)”, Ifremer, Brest, France.
Projet Scientifique :	Integrated structural study of the archaeal replisome
Profil et compétences recherchées:	Applicants should hold a PhD in the area of structural biology, biochemistry, or molecular biology. The ideal candidate has experience in the expression and purification of large multiprotein complexes, and has an interest in acquiring experience in single particle analysis cryo-EM sample preparation and data processing. The position is available immediately, but the starting date is flexible.
Durée du contrat :	2 years
Contact :	Please contact Ludovic Sauguet and Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser. directly with informal inquiries about the position