Intitulé du poste : | Two Post-doctoral positions |
Ville : | Paris-Saclay |
Laboratoire/Institut : | ChemSyBio laboratory, Université Paris-Saclay, INRAE (Micalis Institute) These projects will be performed in the vibrant scientific environment of Université Paris-Saclay, one of the world’s leading university with unique access to major research infrastructures. |
Projet Scientifique : |
The successful candidates will join a dynamic and inter-disciplinary team headed by Dr Olivier Berteau & Dr Alhosna Benjdia, to investigate a novel superfamily of metallo-enzymes. These enzymes catalyze a wide range of chemically challenging reactions, some of which having no counterpart in synthetic chemistry and play a central role in major biosynthetic pathways including cofactor, vitamins and antibiotics biosynthesis. The proposed project aims at gaining a deeper understanding of the unique mechanisms of these emerging biocatalysts but also to develop unprecedented catalytic approaches. The post-doctoral researches will study novel enzymes using either biochemical, bio-physical and/or structural biology approaches. Access to state-of-the-art research facilities will be provided. The post-doctoral researchers will benefit from a collaborative, international and multi-disciplinary scientific environment that values innovation and creativity. |
Profil et compétences recherchées: | The candidates should hold a PhD in Biochemistry, Enzymology, Structural biology or related fields. Experience in molecular biology, protein purification, enzyme kinetics or protein crystallization will be an asset. Skills in physico-chemical techniques (e.g. HPLC, mass spectrometry) will be also beneficial. |
Durée du contrat : | a renewable one year period with a salary commensurate to professional experience. |
Début du contrat : | 1st of July |
Contact : |
2 Post-doctoral positions, Université Paris-Saclay, Biochemistry and Structural Biology
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